Peer-reviewed veterinary case report
Malassezia pachydermatis types and enzyme levels in dogs with skin
By Machado, Mauro L S et al.·Published in Medical mycology·2010·Veterinary Hospital of the Universidade Federal do Rio Grande do Sul, Brazil·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Genetic variability and phospholipase production of Malassezia pachydermatis isolated from dogs with diverse grades of skin lesions.
- Species:
- dog
Plain-English summary
A group of dogs with skin problems, including dermatitis, were studied to understand the types of Malassezia pachydermatis yeast present on their skin. Researchers found different genetic variants of this yeast in both healthy dogs and those with skin lesions. While the yeast was more likely to produce a substance called phospholipase in dogs with skin issues, there was no clear link between the yeast types and the severity of the skin damage. This suggests that environmental factors may play a role in the types of yeast found on dogs' skin.
People also search for: dog skin problems yeast infection · dog dermatitis treatment · why is my dog itching · Malassezia in dogs · dog skin lesions causes
Abstract
Little detailed information is available on the association of Malassezia pachydermatis genotypes and the extent of skin damage that they cause. In the present study, isolates of M. pachydermatis, recovered from the skin of healthy dogs and dogs with dermatitis in Brazil, were characterized on the basis of partial sequencing of the large subunit (LSU), first internal transcribed spacer (ITS-1) and chitin synthase 2 gene (chs-2). The determination of phospholipase production was also included in the investigations. The severity of lesions and hyperpigmentation of dogs with skin disease were evaluated. For each locus, two main sequence types were designated as genotypes A and C. Two other minor sequence types (A2(I)-C2(I)) were also recorded and defined for the ITS-1. Genotype A isolates were the most prevalent, being recovered from healthy and diseased animals. No significant difference was detected among genotypes or ITS-1 sequence types and grades of skin damage or hyperpigmentation in the dogs with skin lesions. The number of M. pachydermatis isolates that produced phospholipase was statistically higher for diseased dogs than for strains found in healthy animals. The present study reveals that multiple genetic variants of M. pachydermatis occur in dogs and that the distribution patterns of particular genotypes on the skin of dogs in Brazil might be related to environmental and ecological factors which maintain distinctive genotype assemblages in specific geographical areas.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20105099/