Peer-reviewed veterinary case report
Genomic Characterization of a Wild-Type(BoAHV-1) Strain Isolated in an Outbreak in Central Italy.
- Journal:
- Viruses
- Year:
- 2024
- Authors:
- Petrini, Stefano et al.
- Affiliation:
- National Reference Centre for Infectious Bovine Rhinotracheitis (IBR) · Italy
Abstract
(BoAHV-1) infection is common in cattle worldwide. However, information on the spread of BoAHV-1-circulating strains in Italy remains limited. In this study, we investigated an outbreak characterized by severe respiratory symptoms in a cattle herd (= 30) located in Central Italy. BoAHV-1 was isolated from three cattle in a cell culture, which confirmed viral infection. Next, we characterized one (16453/07 TN) of the three isolates of BoAHV-1 using whole-genome sequencing. BLASTn and phylogenetic analysis revealed a nucleotide identity >99% with all BoAHV-1 strains belonging to subtype 1.1, highlighting the genetic stability of the virus. This study reports the first full genomic characterization of a BoAHV-1 isolate in Italy, enriching our understanding of the genetic characteristics of the circulating BoAHV-1 strain in Italy.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38275960/