Peer-reviewed veterinary case report
Genomic structure of the Aeromonas bacteriophage pAh6-C and its comparative genomic analysis.
- Journal:
- Archives of virology
- Year:
- 2015
- Authors:
- Jun, Jin Woo et al.
- Affiliation:
- Institute of Marine Biology
Abstract
pAh6-C is a virulent bacteriophage (phage), isolated from a river in Korea, that infects a multiple-antibiotic-resistant A. hydrophila strain, JUNAH. The double-stranded DNA genome of pAh6-C is composed of 53,744 bp with a G + C content of 52.83 %. The genome encodes 86 putative ORFs, four putative promoters, and seven transcriptional terminator regions. Genome sequence analysis of pAh6-C and comparative analysis with the homologous Shewanella phage Spp001 revealed that there is a high degree of similarity between pAh6-C and Spp001 in 50 of the 86 ORFs of pAh6-C. The results of this investigation indicate that pAh6-C is closely related to Spp001, especially in the genes coding for proteins involved in DNA metabolism.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25189428/