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Peer-reviewed veterinary case report

Genomics and vaccine development.

Journal:
Revue scientifique et technique (International Office of Epizootics)
Year:
2007
Authors:
Gay, C G et al.
Affiliation:
United States Department of Agriculture · United States

Plain-English summary

Recent advancements in technology are helping scientists study the genetic material of germs and animals more closely. This research is improving our understanding of how these germs work, how animals' immune systems respond, and how they interact with each other. These new tools can be used to develop better vaccines for farm animals and poultry, which could help protect them from diseases. Overall, this work aims to create more effective vaccines to keep livestock healthy.

Abstract

The current explosion in new high-throughput technologies arising from microbial and animal genomics studies is enabling the analysis of the genome, transcriptome, and proteome and offers the opportunity to gain a better understanding of the molecular pathways underlying pathogen biology, the host immune system, and host-pathogen interactions. These new tools can be applied to veterinary pathogens to overcome some of the current hurdles in the discovery of highly effective vaccines for farmed livestock and poultry.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17633293/