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Peer-reviewed veterinary case report

Canine distemper virus strains in Brazil dogs from 2008 to 2012

By Budaszewski, Renata da Fontoura et al.·Published in Virus research·2014·Laborat&#xf3, Brazil·View original on PubMed

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Original publication title: Genotyping of canine distemper virus strains circulating in Brazil from 2008 to 2012.

Species:
dog

Plain-English summary

A study found that many dogs in Brazil were infected with canine distemper virus (CDV), a serious illness that can affect both vaccinated and unvaccinated dogs. Out of 386 dogs tested, 155 were positive for the virus, with 90 showing symptoms like coughing and fever, while 37 were asymptomatic. Some of the infected dogs had been fully vaccinated, while many had no vaccination history at all. The research highlighted the importance of vaccination and better control measures to protect dogs from this dangerous virus.

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Abstract

Canine distemper virus (CDV) is a major pathogen of dogs and represents a serious threat to both unvaccinated and vaccinated animals. This study surveyed dogs with or without clinical signs related to canine distemper from different regions of Brazil from 2008 to 2012. A total of 155 out of 386 animals were found to be CDV positive by RT-PCR; 37 (23.8%) dogs were asymptomatic at the time of sampling, and 90 (58%) displayed clinical signs suggestive of distemper. Nineteen (12.2%) dogs had a record of complete vaccination, 15 (9.6%) had an incomplete vaccination protocol, and 76 (49%) had no vaccination record. Based on the sequence analysis of the complete hemagglutinin gene of 13 samples, 12 of the strains were characterized as Genotype South America-I/Europe. Considering criteria of at least 95% nucleotide identity to define a genotype and 98% to define a subgenotype, South America-I/Europe sequences segregated into eight different phylogenetically well-defined clusters that circulated or co-circulated in distinct geographical areas. Together, these findings highlight the relevance of CDV infection in Brazilian dogs, demonstrate the predominance of one genotype in Brazil and support the need to intensify the current control measures.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24370870/