Peer-reviewed veterinary case report
Ginseng polysaccharides help reduce inflammatory bowel disease in dogs
By Xie, Liuwei et al.·Published in Frontiers in veterinary science·2025·College of Police Dog Technology, China·View original on PubMed →
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Original publication title: Ginseng polysaccharides ameliorate DSS-induced inflammatory bowel disease by regulating gut microbiota in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with inflammatory bowel disease (IBD) showed improvement after being treated with ginseng polysaccharides, a natural supplement. The dogs had symptoms like gastrointestinal distress, but after treatment, their symptoms lessened, and their gut health improved. Blood tests showed reduced inflammation, and the balance of gut bacteria became healthier. This suggests that ginseng polysaccharides could be a helpful option for managing IBD in dogs, potentially improving their overall health and quality of life.
People also search for: dog inflammatory bowel disease treatment · ginseng for dog gut health · dog IBD symptoms and remedies
Abstract
Inflammatory bowel disease (IBD) is a common chronic gastrointestinal disorder in dogs that seriously affects health and quality of life. This study evaluated the effects of ginseng polysaccharides on dextran sodium sulfate (DSS)-induced IBD in dogs, with emphasis on clinical symptoms, serum parameters, and gut microbiota. Our findings revealed that treatment with ginseng polysaccharides alleviated clinical symptoms, improved colonic histopathology, and partially restored serum biochemical changes, including a significant reduction in C-reactive protein. Microbiota analysis showed increased alpha diversity and recovery of community composition, with enrichment of beneficial genera such as,, and, and reduction of. Functional prediction indicated that ginseng polysaccharides reversed DSS-associated suppression of carbohydrate metabolism pathways. These findings suggest that ginseng polysaccharides mitigate DSS-induced IBD in dogs by modulating inflammation and gut microbiota composition, supporting their potential as a natural therapeutic candidate for canine IBD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41585527/