Peer-reviewed veterinary case report
Seven-month-old Golden Retriever with brain tumor causing low thirst
By Engel, Stephanie et al.·Published in Journal of the American Animal Hospital Association·2016·From the Clinical Sciences Department (S.E.), United States·View original on PubMed →
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Original publication title: Glioblastoma Multiforme with Hypodipsic Hypernatremia in a Seven-Month-Old Golden Retriever.
- Species:
- dog
Plain-English summary
A 7-month-old Golden Retriever was brought in with severe thirst issues and high sodium levels in the blood, a condition known as hypodipsic hypernatremia. The veterinarian discovered that the cause was a brain tumor called glioblastoma multiforme, which was affecting the dog's ability to feel thirsty. This type of tumor is quite rare in such a young dog. Unfortunately, due to the aggressive nature of the tumor and its impact on the dog's health, treatment options were limited, and the prognosis was poor.
People also search for: dog thirst problems · Golden Retriever brain tumor · glioblastoma treatment in dogs
Abstract
Primary hypodipsic hypernatremia is a rarely reported disease in dogs. Reported underlying causes associated with this disease in dogs include congenital malformations, encephalitis, intracranial neoplasia, and pressure atrophy of the hypothalamus secondary to hydrocephalus. The dog in this report had an infiltrative neoplastic disorder, likely causing damage to the hypothalamic osmoreceptors responsible for the thirst generation. The neoplastic process was identified histopathologically as glioblastoma multiforme, an unusual tumor to occur in a dog this young. A tumor of the central nervous system causing physical destruction of the osmoreceptors has rarely been reported in dogs and none of the previously reported cases involved a glial cell tumor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27487344/