Peer-reviewed veterinary case report
Labrador with low cortisol and low blood cells mimicking sepsis
By Snead, Elisabeth et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2011·Department of Small Animal Clinical Sciences, Canada·View original on PubMed →
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Original publication title: Glucocorticoid-dependent hypoadrenocorticism with thrombocytopenia and neutropenia mimicking sepsis in a Labrador retriever dog.
- Species:
- dog
Plain-English summary
A 3-year-old Labrador retriever was brought in with symptoms that looked like a severe infection, including low blood cell counts. After tests, the vet diagnosed the dog with glucocorticoid-deficient hypoadrenocorticism (a condition where the adrenal glands don't produce enough hormones) along with immune-mediated thrombocytopenia (low platelets) and neutropenia (low white blood cells). This combination is rare in dogs and can be tricky to identify. Treatment typically involves hormone replacement and managing the immune response, which can help the dog recover and feel better.
People also search for: dog low blood cell count · Labrador retriever adrenal gland disease · hypoadrenocorticism treatment in dogs
Abstract
Glucocorticoid-deficient hypoadrenocorticism (GDH) with immune-mediated-neutropenia (IMN) and -thrombocytopenia (IMT) were diagnosed in a 3-year-old Labrador retriever dog. Glucocorticoid-deficient hypoadrenocorticism is rare and diagnostically challenging as clinical signs and laboratory abnormalities are often nonspecific. Immune-mediated cytopenias and other autoimmune disorders, as part of an autoimmune polyglandular syndrome have been reported with hypoadrenocorticism in humans. This is the first reported case of hypoadrenocorticism and bicytopenia in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22467971/