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Peer-reviewed veterinary case report

Glucose and Insulin Tolerance Tests in the Mouse.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2015
Authors:
Vinué, Ángela & González-Navarro, Herminia
Affiliation:
Institute of Health Research-INCLIVA · Spain

Abstract

In vivo metabolic tests are highly valuable to determine whether atherosclerosis progression in mouse models is accompanied by carbohydrate metabolism alterations such as glucose intolerance and insulin resistance. In this chapter, we describe protocols to perform in the mouse glucose and insulin tolerance tests, two metabolic assays which evaluate the glucose tolerance and the insulin sensitivity, respectively.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/26445794/