Peer-reviewed veterinary case report
Glaucoma linked to eye drainage defect in adult European Short-haired
By Trost, Katrin et al.·Published in Veterinary ophthalmology·2007·Department for Small Animals and Horses·View original on PubMed →
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Original publication title: Goniodysgenesis associated with primary glaucoma in an adult European Short-haired cat.
- Species:
- cat
Plain-English summary
A 9.5-year-old male European Short-haired cat was brought in for problems with both eyes, including high pressure and pain due to glaucoma. Despite treatment over 1.5 years, the right eye became blind and was removed, while the left eye underwent laser treatment but continued to lose vision. The issue was linked to a developmental problem in the eye's drainage system, which caused the glaucoma. Unfortunately, the treatments did not fully restore vision, and the cat experienced progressive eye issues.
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Abstract
A 9.5-year-old, male castrated European Short-haired (ESH) cat was presented with bilateral glaucoma associated with pectinate ligament dysplasia and an open iridocorneal angle (ICA) upon gonioscopy. The right eye (OD) was avisual and slightly enlarged; the left eye (OS) was still visual. Intraocular pressure (IOP) had been controlled with medical therapy over a 1.5 year-period in both eyes (OU). Eventually IOP could not be adequately controlled medically and the painful and blind right eye was enucleated and transscleral diode laser cyclophotocoagulation was performed twice in the left eye with less than optimal results and progressive loss of vision. Histopathology of the right eye showed goniodysgenesis characterized by failure of differentiation of the pectinate ligament, which existed as a solid sheet of uveal tissue at the entrance of a hypoplastic ciliary cleft, which contained loose mucoid mesenchymal tissue. The trabecular meshwork was hypoplastic and the scleral venous plexus could not be identified. Other findings of chronic glaucoma were inner retinal atrophy, optic nerve atrophy with disc cupping, scleral thinning, peripheral corneal vascularization and pigmentation, and mild focal iridal mononuclear inflammatory cell infiltrate.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17973828/