Peer-reviewed veterinary case report
Brain tumors causing neurological signs in two dogs and their
By Higgins, R J et al.·Published in Veterinary pathology·2001·Department of Pathology, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Granular cell tumor of the canine central nervous system: two cases.
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog and a 10-year-old Labrador were brought in for neurological issues, including changes in behavior and coordination. Both dogs had brain tumors called granular cell tumors, which were confirmed through biopsies. The tumors were surgically removed, but the outcomes varied; the mixed-breed dog lived for a year after surgery, while the Labrador survived for four months. This highlights the importance of early diagnosis and treatment for brain tumors in dogs, but outcomes can differ significantly.
People also search for: dog brain tumor symptoms · granular cell tumor in dogs · dog surgery for brain tumor · neurological signs in dogs
Abstract
Although pure granular cell tumors have been reported in various sites in the dog, only one tumor has been reported in the central nervous system. Two dogs presented with neurologic signs had brain lesions detected by magnetic resonance imaging in the area of the olfactory bulbs and frontal cortex. In both dogs, a clinical diagnosis of a granular cell tumor was made from tissues obtained from stereotactic biopsies guided by computed tomography. Surgical removal of the tumors was followed by histopathologic, ultrastructural, and immunocytochemical characterization. Although not conclusive, these studies indicated that the granular cells were not of leucocyte origin but may have been derived from the meninges. One dog died 12 months after surgery, and the other was alive 4 months later.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11732794/