Peer-reviewed veterinary case report
Granulomatous enteritis and cutaneous arteritis in a horse.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1993
- Authors:
- Woods, P R et al.
- Affiliation:
- Department of Large Animal Medicine and Surgery · United States
- Species:
- horse
Plain-English summary
A 5-year-old Quarter Horse mare was taken to the vet because she had been losing weight for two months. She was found to be anemic, in poor shape, and had several sores on her skin, including on her face and legs. Tests showed she had trouble absorbing nutrients from her food, and a biopsy of her skin lesions indicated inflammation of the blood vessels. The mare was treated with prednisone, a type of steroid, but unfortunately, she did not get better and was humanely put to sleep. A post-mortem examination revealed she had a serious intestinal condition called granulomatous enteritis, which is similar to a digestive issue seen in humans.
Abstract
A 5-year-old Quarter Horse mare was examined because of weight loss of 2 months' duration. The horse was anemic and in poor body condition, and had several areas of cutaneous ulceration, including areas on the muzzle and distal portion of the limbs. Histologic examination of a rectal mucosa biopsy specimen revealed a lymphoplasmacytic infiltrate in the lamina propria mucosa. Results of a glucose absorption test were suggestive of malabsorption. Histologic examination of a biopsy specimen from the cutaneous lesions revealed pronounced arteritis, and weak, patchy immunofluorescent staining for immunoglobulins at the basement membrane. The horse was treated with prednisone, but did not improve, so the horse was humanely destroyed. Necropsy revealed granulomatous enteritis. This case identified an unusual combination of clinical problems and suggests further evidence for similarities between equine granulomatous enteritis and regional enteritis in human beings.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8288481/