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Peer-reviewed veterinary case report

Granulomatous meningoencephalitis and blindness associated with Mycobacterium tuberculosis complex infection in a senile female chimpanzee (Pan troglodytes).

Journal:
Journal of medical primatology
Year:
2024
Authors:
Dos Santos, Daniel Oliveira et al.
Affiliation:
Escola de Veterin&#xe1 · Brazil

Abstract

A 40-year old female chimpanzee (Pan troglodytes) developed hyporexia, weight loss, followed by progressive and complete blindness. Tomography demonstrated an intracranial mass in the rostroventral brain involving the optic chiasm, with a presumptive diagnosis of neoplasm. However, histopathology revealed a granulomatous meningoencephalitis, and tissue samples tested positive for Mycobacterium tuberculosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38706108/