Peer-reviewed veterinary case report
Cannabidiol use for eye disease in dogs has limited evidence
By Henriksen, Michala de Linde & McGrath, Stephanie·Published in Journal of the American Veterinary Medical Association·2024·Department of Clinical Sciences·View original on PubMed →
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Original publication title: Growing interest but limited evidence on the usefulness of cannabidiol in treating ophthalmic disease in dogs: a review.
- Species:
- dog
Plain-English summary
A growing interest in using cannabidiol (CBD) for treating eye problems in dogs has emerged, but there is still limited evidence on its effectiveness. CBD, a non-psychoactive compound from the hemp plant, is being explored for its potential benefits in conditions like glaucoma and corneal diseases. While some studies suggest that CBD may help reduce inflammation and protect nerve health, more research is needed to confirm its safety and efficacy for these specific eye issues in dogs. Pet owners should consult their veterinarian before considering CBD for their dog's eye problems.
People also search for: dog eye problems treatment · CBD for dog glaucoma · canine corneal disease treatment
Abstract
The 2 most known cannabinoids are Δ9-tetrahydrocannabidiol (THC) and cannabidiol (CBD). Both chemicals are extracted from the cannabis plant but can also be synthetically produced. Δ9-Tetrahydrocannabidiol is extracted from the subspecies of the cannabis plant known as the marijuana plant, which contains a high concentration of THC (0.3% to 30%). Δ9-Tetrahydrocannabidiol is a major psychoactive and intoxicating component of the cannabis plant and is not recommended for use in dogs due to its toxic effect. Cannabidiol is extracted from the subspecies of the cannabis plant known as the hemp plant and must contain less than 0.3% THC. Cannabidiol is a major nonpsychoactive component of the cannabis plant, and its effect has been investigated for epilepsy, neoplasia, and osteoarthritis in dogs. Public interest in the medical use of cannabinoids for various diseases and disorders has grown in the last couple of years. The attention has extended to veterinary medicine, where veterinarians and pet owners are curious about what diseases the nontoxic CBD can be used for to treat companion animals. The use of CBD for ophthalmic diseases has also been investigated due to its anti-inflammatory and neuroprotective effects. Intraocular pressure regulation for glaucoma, corneal diseases (eg, keratitis and corneal pain), uveal diseases (eg, endotoxin-induced uveitis), and retinal/optic nerve head diseases (eg, diabetic retinopathy) are areas where CBD's effect has been investigated in humans and animals. The aim of this review is to give an update on what is known regarding the use of cannabinoids, especially CBD, for ophthalmic diseases in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39236742/