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Peer-reviewed veterinary case report

Canine adenocarcinoma cells grew in aerobic bacterial culture

By Dusick, Allison F et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2020·School of Veterinary Medicine·View original on PubMed

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Original publication title: Growth of adenocarcinoma from canine pleural fluid on aerobic bacterial culture.

Species:
dog

Plain-English summary

A 10-year-old mixed-breed dog was diagnosed with adenocarcinoma, a type of cancer, after fluid was collected from its chest. The fluid showed suspicious cells, and when cultured, these cells grew into colonies that matched the cancerous cells found in other tests. Unfortunately, the cancer had spread to multiple organs, including the pancreas and lungs, and the dog passed away. This case highlights the importance of examining pleural fluid for signs of cancer in dogs.

People also search for: dog cancer symptoms · pleural effusion in dogs · adenocarcinoma treatment for dogs

Abstract

We report a case of canine adenocarcinoma with multi-organ metastasis in which colonies of adenocarcinoma cells grew upon aerobic bacterial culture of pleural effusion. Stained agar colonies were highly similar to rare suspicious cells seen on cytologic examination of the pleural effusion, as well as rare cells seen on cytologic examination of pancreatic and gastric wall fine-needle aspirates. Cells from colonies growing on agar media were mildly immunoreactive for cytokeratin. Histologic examination of tissues obtained at autopsy revealed pancreatic adenocarcinoma with vascular invasion and nodal, gastric, pulmonary, and pleural metastasis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31744399/