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Peer-reviewed veterinary case report

Dog with fatal H3N2 canine flu and lung infection in Chicago 2015

By Watson, C E et al.·Published in Veterinary pathology·2017·University of Wisconsin-Madison, United States·View original on PubMed

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Original publication title: H3N2 Canine Influenza Virus Infection in a Dog.

Species:
dog

Plain-English summary

A 10-year-old German Shepherd was brought to the vet because he was very tired and coughing, but sadly, he passed away shortly after. The dog was found to have H3N2 canine influenza, a serious virus that was spreading in the Chicago area at the time. Tests showed severe damage in his lungs and other respiratory areas, along with bacterial infections. Unfortunately, despite the findings, there was no successful treatment to save him.

People also search for: dog coughing lethargy · canine influenza symptoms · H3N2 dog treatment

Abstract

In 2015, H3N2 canine influenza emerged in dogs in the greater Chicago area. During this time, a 10-year-old German Shepherd dog presented to the referring veterinarian with lethargy and coughing that quickly progressed to death. This report describes the macroscopic and microscopic lesions and the molecular testing performed to identify the novel North American H3N2 strain of canine influenza. The larynx, pharynx, and trachea were covered by a fibrinonecrotic membrane. Bilaterally, the lungs had multifocal subpleural necrosis of the caudal lung lobes with hemorrhage, congestion, and pulmonary edema. Staphylococcus pseudointermedius was isolated from the lung. Mycoplasma cynos was identified by real-time polymerase chain reaction from nasal passages, oropharynx, larynx, trachea, and cranial lung lobes. The neuraminidase gene sequence from the influenza virus isolated obtained from this dog had ≥98% homology to the strain circulating in the Chicago area.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28438112/