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Peer-reviewed veterinary case report

Haemophilia A (factor VIII deficiency) in a litter of Weimaraners.

Journal:
The Journal of small animal practice
Year:
2009
Authors:
Dunning, M D et al.
Affiliation:
Department of Veterinary Medicine · United Kingdom
Species:
dog

Abstract

Inherited coagulopathies are reported in a number of dog breeds. However, to date, there is no report of Weimaraners suffering factor VIII deficiency (haemophilia A). We report the discovery of haemophilia A in both males from a single litter of Weimaraners. Haemophilia A in human beings often results from a de novo stochastic mutation. We found no evidence using currently available screening tests of haemophilia A in relatives as far back as three generations making a stochastic mutation possible in this litter.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19508492/