Peer-reviewed veterinary case report
Haemophilia A bleeding disorder found in Weimaraner puppies
By Dunning, M D et al.·Published in The Journal of small animal practice·2009·Department of Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Haemophilia A (factor VIII deficiency) in a litter of Weimaraners.
- Species:
- dog
Plain-English summary
Two male Weimaraner puppies from the same litter were found to have a bleeding disorder called haemophilia A, which is caused by a deficiency in factor VIII. This condition is rare in this breed, and there was no history of it in their family for at least three generations, suggesting it may have occurred due to a new genetic mutation. Owners of these puppies should be aware of the potential for bleeding issues and discuss any concerns with their veterinarian for proper management and care.
People also search for: Weimaraner bleeding disorder · haemophilia A in dogs · puppy bleeding problems
Abstract
Inherited coagulopathies are reported in a number of dog breeds. However, to date, there is no report of Weimaraners suffering factor VIII deficiency (haemophilia A). We report the discovery of haemophilia A in both males from a single litter of Weimaraners. Haemophilia A in human beings often results from a de novo stochastic mutation. We found no evidence using currently available screening tests of haemophilia A in relatives as far back as three generations making a stochastic mutation possible in this litter.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19508492/