Peer-reviewed veterinary case report
Female mixed-breed dog with bleeding disorder haemophilia
By Nishitani, Y & Kitoh, K·Published in The Journal of small animal practice·2021·Joint Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Haemophilia A in a female mixed-breed dog.
- Species:
- dog
Plain-English summary
A spayed female mixed-breed dog was brought in because she was bleeding excessively from a wound in her mouth. She had previously experienced some bleeding after a surgery, but this episode was more severe. Tests showed that her blood took longer to clot due to very low levels of a protein called factor VIII, which is crucial for blood clotting. The dog was diagnosed with haemophilia A, a genetic bleeding disorder. Treatment options may include managing her bleeding episodes and monitoring her condition closely.
People also search for: dog bleeding disorder · haemophilia A in dogs · dog mouth wound treatment · why is my dog bleeding excessively
Abstract
A spayed female mixed-breed dog was presented with excessive bleeding from a wound in the mouth. The dog had a history of self-limiting bleeding following ovariohysterectomy. A coagulation test revealed prolongation of the activated partial thromboplastin time (20.2 seconds; reference interval: 11.0-15.0 seconds), prothrombin time was normal and factor VIII activity was markedly decreased (1.9%; reference interval: >50%). The von Willebrand factor antigen concentration was 158% (reference interval: >50%). A cross-mixing test indicated that the diminished factor VIII activity was due to deficiency or dysfunction of factor VIII rather than inhibition of factor VIII activity. Based on these results, the dog was diagnosed with haemophilia A. Haemophilia A should be considered in the differential diagnosis of bleeding disorders also in female mixed-breeds dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32716072/