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Peer-reviewed veterinary case report

Helicobacter pylori protein oxidation influences the colonization process.

Journal:
International journal of medical microbiology : IJMM
Year:
2006
Authors:
Godlewska, Renata et al.
Affiliation:
Department of Bacterial Genetics
Species:
rodent

Abstract

Dsb proteins control the formation and rearrangement of disulfide bonds during the folding of membrane and exported proteins. Here we examined the role of DsbI protein in Helicobacter pylori pathogenesis and demonstrated that a dsbI mutant impaired in disulfide bond formation revealed a greatly reduced ability to colonize mice gastric mucosa.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16545604/