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Peer-reviewed veterinary case report

Hemangiosarcoma and squamous cell carcinoma in the third eyelid of a horse.

Journal:
Veterinary ophthalmology
Year:
2007
Authors:
Gearhart, Patricia M et al.
Affiliation:
Department of Small Animal Clinical Sciences · United States
Species:
horse

Plain-English summary

A 12-year-old Belgian draft horse had a growth on the third eyelid of its right eye, along with some red-tinged discharge, for about three months. The growth was surgically removed and tested, revealing it contained both hemangiosarcoma (a type of cancer that affects blood vessels) and squamous cell carcinoma (a type of skin cancer). About 16 months after the surgery, the horse developed thickened eyelids and more bleeding from the eye, which led to the decision to euthanize it. A post-mortem examination confirmed that the cancer had returned and spread to nearby areas. This case was notable because it involved two different types of cancer in the same mass, which couldn't be identified just by looking at it.

Abstract

A 12-year-old Belgian draft horse presented for a right eye third eyelid mass and red-tinged ocular discharge of 3 months' duration. The third eyelid was excised and submitted for histopathology. On histopathologic examination, the mass was composed of both hemangiosarcoma and squamous cell carcinoma. The horse developed thickened eyelids and hemorrhagic ocular discharge from the right eye approximately 16 months following surgery, and was euthanized. Necropsy and histopathology confirmed local recurrence and regional metastasis of the hemangiosarcoma. This was an unusual case because there were two distinct neoplastic processes composing the same mass that could not be differentiated grossly.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17324168/