Peer-reviewed veterinary case report
Blood volume replacement effects with saline and starch in dogs
By Udelsmann, Artur et al.·Published in Acta cirurgica brasileira·2009·Department of Anesthesiology and Laboratory of Experimental Anesthesia, Brazil·View original on PubMed →
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Original publication title: Hemodynamic effects of volume replacement with saline solution and hypertonic hydroxyethyl starch in dogs.
- Species:
- dog
Plain-English summary
A group of dogs that had lost blood were given either a saline solution or a special fluid called hypertonic hydroxyethyl starch to see which helped their blood pressure and circulation more effectively. Both treatments helped the dogs recover to normal levels, but the hypertonic hydroxyethyl starch worked faster and provided more stable results. This means that for dogs experiencing low blood volume, the hypertonic solution might be a better option for quick recovery.
People also search for: dog blood loss treatment · saline vs hypertonic solution for dogs · dog blood pressure recovery
Abstract
PURPOSE: To investigate hemodynamic response to volume replacement with saline solution and hypertonic hydroxyethyl starch in hypovolemic dogs. METHODS: Forty dogs under general anesthesia and hemodynamic monitoring, following measurements at baseline, were bled 20 ml x Kg(-1) and parameters were measured again after 10 minutes. The animals were randomly divided in two groups and volume replacement was performed with saline solution twice the volume removed or 4 ml x Kg(-1) of hypertonic hydroxyethyl starch. Hemodynamic data were again measured after 5, 15, 30, 45 and 60 minutes. RESULTS: With both solutions values returned to satisfactory hemodynamic levels. With saline solution, there was a greater amplitude in variations that tended to decrease progressively. With hypertonic hydroxyethyl starch, the parameters studied returned more rapidly to levels similar to those at baseline and varied less. CONCLUSION: Both solutions proved to be efficient at replacing volume in the short period studied, although hypertonic hydroxyethyl starch produced more stable results.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19377775/