Peer-reviewed veterinary case report
Bleeding crisis in 6-month-old male dog treated with plasma
By Mischke, R et al.Ā·Published in DTW. Deutsche tierarztliche WochenschriftĀ·1996Ā·Klinik fü, GermanyĀ·View original on PubMed ā
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Original publication title: [Hemophilia B in a mixed breed male dog: treatment of a hemorrhagic crisis with fresh frozen plasma].
- Species:
- dog
Plain-English summary
A 6-month-old male mixed breed dog developed a large bruise on his left thigh without any obvious injury. Tests showed that he had a bleeding disorder called hemophilia B, which means his blood didn't clot properly due to low levels of a specific clotting factor. The vet treated him with two infusions of fresh frozen plasma, which helped improve his condition significantly. After the treatment, the dog's bleeding issues were resolved, and he showed clear signs of recovery.
People also search for: dog bruise without injury Ā· hemophilia B treatment in dogs Ā· fresh frozen plasma for dog bleeding
Abstract
A 6 months old male crossbred dog became conspicuous because of a considerable haematoma in the region of the left thigh without recognizable exterior trauma. The results of the screening tests of the haemostatic system (distinctly prolonged activated partial thromboplastin time [aPTT], normal thromboplastin time and platelet count as well as a shortening of thrombin time) yielded a tentative diagnosis of haemophilia. Haemophilia B could be diagnosed on the basis of a distinctly and isolated reduced factor IX activity (8%, reference range: 70-140%). Two infusions with 20 ml/kg BW fresh frozen plasma each caused a clear clinical recovery of the patient. In addition, the efficacy of plasma infusion was documented in vitro by a temporary increase of factor IX activity as well as repeated measurements with the resonance thrombograph and of the aPTT.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8647012/