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Peer-reviewed veterinary case report

Ultrasound shows liver changes in dogs with hepatocutaneous syndrome

By Jacobson, L S et al.·Published in Journal of veterinary internal medicine·1995·Department of Medicine·View original on PubMed

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Original publication title: Hepatic ultrasonography and pathological findings in dogs with hepatocutaneous syndrome: new concepts.

Species:
dog

Plain-English summary

Three dogs were diagnosed with hepatocutaneous syndrome, a condition that causes skin problems like sores and crusts due to liver disease. The dogs showed typical skin changes, and tests revealed unusual liver patterns that looked like Swiss cheese on ultrasound. This condition is linked to liver damage and certain metabolic issues. The findings from the ultrasound matched what was seen in the liver tissue samples. Treatment details weren't specified, but recognizing the skin signs and liver issues is crucial for managing this serious condition.

People also search for: dog skin sores liver disease · hepatocutaneous syndrome in dogs · dog liver ultrasound results

Abstract

In dogs, hepatocutaneous syndrome (superficial necrolytic dermatitis) belongs to a group of syndromes in which cutaneous signs signal the presence of systemic disease. It is characterized by parakeratosis, superficial necrolysis, and basilar hyperplasia of the epidermis, in association with an unusual hepatopathy accompanied by certain metabolic derangements. Hepatocutaneous syndrome was diagnosed in 3 dogs on the basis of typical dermatologic changes and clinicopathologic findings. Hepatic ultrasonography revealed a hyperechoic network surrounding hypoechoic areas of parenchyma, resulting in a Swiss cheese-like appearance. The ultrasonographic image corresponded to the pathological findings. The liver had a nodular appearance, both grossly and microscopically; this was attributed to collapse of the areas of parenchyma surrounding the nodules, rather than to the cirrhosis and/or nodular hyperplasia reported previously.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8558487/