Peer-reviewed veterinary case report
Hepatoprotective Activity.
- Journal:
- Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques
- Year:
- 2016
- Species:
- rodent
Abstract
The liver performs a vital role in metabolism, secretion, storage, and detoxification of endogenous and exogenous substances. Oxidative stress and free radicals enhance the severity of hepatic damage, which can be overcome by the antioxidant mechanism. Plant extracts can be the best source of such antioxidants and mediate hepatoprotective activity. In this chapter, high-dose paracetamol-induced hepatotoxicity in rat model is discussed with explanations of biochemical and histopathological studies.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26939279/