Peer-reviewed veterinary case report
Hepatoprotective activity of Phyllanthus reticulatus.
- Journal:
- Pakistan journal of pharmaceutical sciences
- Year:
- 2008
- Authors:
- Das, Biplab K et al.
- Affiliation:
- Department of Pharmacy
- Species:
- rodent
Abstract
Two partially purified organic fractions designated by PR1 and PR2 of the fat free ethanol (95%) extract of aerial parts of Phyllanthus reticulatus were tested for the hepatoprotective activity in rats against CCl(4)-induced liver damage. The rats receiving the fractions showed promising hepatoprotective activity as evident from significant changes of pentobarbital-induced sleeping time, changes in serum levels of sGPT, sGOT, sALP and bilirubin and also from histopathological changes as compared to CCl(4)-intoxicated rats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18930851/