Hereditary hyperlipidemia ocular lesions in a decorative domestic rabbit

Abstract

In animals, as in humans, a significant part of the functional or morphological ophthalmic pathologies are associated with general or systemic diseases. Abnormalities detected during ophthalmological examination, in some cases, are symptoms of a general pathological process and can contribute to the diagnosis. The article discusses the clinical case of the eye pathological changes development in a decorative domestic rabbit (Oryctolagus cuniculus domesticus) accompanying a cholesterol metabolism hereditary disorder: chronic lipogranulomatous conjunctivitis, lipid degeneration of the cornea, massive cholesterol infiltration of the sclera fibrous stroma and eyeball posterior pole, hypertrophy of the orbit fatty cellular tissue. The observed pathological processes in the eyes and their adnexal structures were manifestated severely. The article presents MRI data and photographs of histological preparations of pathologically altered tissues. A clinical description of severe ophthalmic abnormalities in rabbit with hereditary hyperlipidemia as in our article, is not presented in the available scientific literature.