Peer-reviewed veterinary case report
HGMT: a database of human gut microbiota for tumors and immunotherapy response.
- Year:
- 2025
- Authors:
- Liu J et al.
- Affiliation:
- Department of Neurology · China
Abstract
HGMT is a database designed to analyze, explore, and visualize gut microbiomes from diverse tumor types. We process metagenomic datasets from 18,630 stool samples across 37 tumor types, including 2,207 samples from immunotherapy-treated patients across 12 tumor types. HGMT provides an interactive portal for querying taxonomic and functional profiles, visualizing cross-dataset differential abundance taxa in tumors, and identifying their pan-tumor associations. Our analysis reveals the capability of gut microbiota in diagnosing gastrointestinal tumors and predicting immunotherapy response for non-small cell lung carcinoma. HGMT represents a valuable resource for investigating the roles of gut microbiota in tumors and immunotherapy response.
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Search related cases →Original publication: https://europepmc.org/article/MED/41286929