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Peer-reviewed veterinary case report

Hidden survivors: Long-lived IgE-secreting plasma cells in the spleen.

Journal:
Immunity
Year:
2025
Authors:
Glaros, Vassilis & Kreslavsky, Taras
Affiliation:
Department of Medicine

Abstract

Until recently, the existence of long-lived IgE-secreting plasma cells was debated. Using timestamping in mouse models of type 2 inflammation, two studies in this issue of Immunity reveal the long-term persistence of IgE-secreting plasma cells in secondary lymphoid organs rather than in the bone marrow.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41223839/