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Peer-reviewed veterinary case report

High-resolution imaging techniques to interrogate virus-host interactions.

Year:
2026
Authors:
Amaya I & Spriggs CC.
Affiliation:
Department of Cell and Developmental Biology · United States

Abstract

Viruses are obligate parasites that rely extensively on host cellular machinery to complete their life cycles. Therefore, examining the fundamental nature behind how viruses interact with their hosts can teach us more about the pathogenesis of these microbes while also contributing to our overall understanding of essential cell biological processes. In a 2021 mSphere of Influence article, the use of live-cell imaging to uncover a unique mechanism of viral assembly was discussed. In this Full Circle review, we highlight the high-resolution imaging techniques currently revolutionizing virology research and discuss how they can be utilized to advance our ability to identify and interrogate novel virus-host interactions.

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Original publication: https://europepmc.org/article/MED/41711433