Peer-reviewed veterinary case report
Fatal widespread nematode infection confirmed in a dog
By Nosková, Eva et al.·Published in Parasitology·2024·Department of Botany and Zoology·View original on PubMed →
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Original publication title: High-throughput sequencing of- a fatal disseminated infection in a dog.
- Species:
- dog
Plain-English summary
A dog in the Czech Republic sadly died from a severe infection caused by a type of roundworm known to affect both humans and dogs. This case was particularly concerning because the infection was linked to the dog's weakened immune system, which was worsened by the use of corticosteroids (a type of medication that suppresses immune response). The infection was confirmed through advanced genetic testing. Unfortunately, despite these findings, the dog did not survive.
People also search for: dog infection symptoms · corticosteroids side effects in dogs · roundworm infection in dogs
Abstract
The rhabditid nematodeis known worldwide as the causative agent of strongyloidiasis in humans. In addition to public health concerns,.also infects dogs, which represent a possible reservoir for potentially zoonotic transmissions. We describe the first confirmed case of fatal disseminated infection in a dog in the Czech Republic. The microscopic and histological results were supported by a complex genotyping approach. Using high-throughput sequencing of the hypervariable region (HVR-IV) of 18S rDNA and Sanger sequencing of the partial cytochrome c oxidase subunit 1 gene (), the potentially zoonotic haplotype/lineage A of.was confirmed, while the solely canine haplotype/lineage B was not found. The development of the disease is mainly associated with immunodeficiency, and in this case, it was triggered by inappropriate treatment, in particular the use of corticosteroids.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38800868/