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Peer-reviewed veterinary case report

Canine Prostatic Specific Esterase (CPSE) for Diagnosing Dog Prostate

By Melandri, Monica & Alonge, Salvatore·Published in Veterinary medicine and science·2021·Societ&#xe0, Italy·View original on PubMed

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Original publication title: Highlights on the Canine Prostatic Specific Esterase (CPSE): A diagnostic and screening tool in veterinary andrology.

Species:
dog
Drinking & peeingDogs

Plain-English summary

A recent study highlights that measuring a specific enzyme called canine prostatic specific esterase (CPSE) in blood can help diagnose prostate problems in dogs. This test can detect issues like benign prostatic hyperplasia (an enlarged prostate), bacterial prostatitis (an infection), and even prostate cancer. It's useful for both diagnosing existing conditions and screening healthy dogs for potential problems. To get accurate results, it's recommended that dogs have a sexual rest of at least 24 hours before the test. This new tool could improve how veterinarians monitor and treat dogs with prostate issues.

People also search for: dog prostate problems test · CPSE blood test for dogs · symptoms of prostate cancer in dogs

Abstract

In the last years, the need to look for an accurate and precise diagnosis of prostatic diseases in dogs has grown. Among other diagnostic tools, the seric CPSE has been studied and identified as a valid and specific biomarker for prostatic disorders, since it can result significantly more elevated in dogs affected by several prostatic abnormalities, such as benign prostatic hyperplasia, bacterial prostatitis and prostatic carcinoma. Therefore, dosing CPSE in serum represents a new diagnostic and screening tool. Dosing CPSE in everyday clinical practice has three objectives: (a) the diagnosis of benign prostatic hyperplasia; (b) the preventive screening of prostatic disorders in healthy dogs; (c) the medical follow-up in subjects with prostatic disorders during and after medical therapy. Neither circadian rhythms nor transrectal palpation performed during the andrological examination do affect CPSE. A sexual rest of at least 24 hr before dosing CPSE is recommended as it is affected by ejaculation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32881401/