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Peer-reviewed veterinary case report

Highly Reliable and Ultraflexible Organic Light-Emitting Diode Patch for Psoriasis Treatment.

Journal:
Advanced healthcare materials
Year:
2026
Authors:
Seo, Yeong Cheol et al.
Affiliation:
School of Electrical Engineering · South Korea

Abstract

Psoriasis is a chronic inflammatory skin disease that significantly affects the quality of life of patients. Photodynamic therapy is effective in treating psoriasis; however, existing light sources, such as lasers and light-emitting diodes (LEDs), have limitations in terms of flexibility, uniformity of light irradiation, and patient convenience. In this study, a high-power ultraflexible organic LED (OLED) patch is fabricated on a PET adhesive film, resulting in a high output of 60 mW cmat 7.5 V. Based on high-performance encapsulation technology, the OLED patch achieved a lifetime of 177 h and no performance change after bending for 10 000 times for a radius of 2 mm at 35 mW cm. Finally, photodynamic therapy is performed in a psoriasis mouse model using an OLED for the first time, and the effect is confirmed through a cross-sectional analysis of the mouse skin, in which the thickness of the diseased area is reduced by 66% compared with the control group.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41367091/