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Peer-reviewed veterinary case report

Dog with histiocytic chorioretinitis causing retinal detachment

By Sherman, Amanda B et al.·Published in Veterinary ophthalmology·2018·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Histiocytic chorioretinitis in a dog.

Species:
dog

Plain-English summary

A 3-year-old mixed-breed dog was brought in with a serious eye problem, showing signs of a detached retina in the right eye. After the eye was removed, tests showed it was not a tumor but a condition called histiocytic chorioretinitis, which is an inflammation of the eye. Later, the left eye also developed a similar issue, but thankfully, treatment with steroids helped restore the dog's vision within a few weeks. This case illustrates how tricky it can be to tell the difference between tumors and inflammation in the eye.

People also search for: dog eye problems · retinal detachment in dogs · dog vision recovery with steroids

Abstract

A 3-year-old castrated male mixed-breed dog presented with an acute bullous retinal detachment and thickened choroid of the right eye. Subretinal cytology revealed an atypical cell proliferation suggestive of neoplasia. The eye was enucleated, and the original diagnosis was a histologically benign choroidal melanocytic tumor. Further diagnostics revealed no other systemic abnormalities other than a nonhealing shoulder wound. Six months later, the left eye developed a bullous retinal detachment. This eye responded well to systemic steroids and the dog regained vision within a few weeks of initiating therapy. Results of immunohistochemistry with Melan-A and CD204 of the previously enucleated right eye caused a revision of the histologic diagnosis from melanocytic tumor to histiocytic chorioretinitis. This case highlights the subtle and sometimes confusing distinction between neoplastic and inflammatory processes on both cytology and histopathology.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27520710/