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Peer-reviewed veterinary case report

Histiocytic sarcoma of the stifle in a dog with cranial cruciate ligament failure and TPLO treatment.

Journal:
Veterinary and comparative orthopaedics and traumatology : V.C.O.T
Year:
2008
Authors:
Harasen, G L G & Simko, E
Affiliation:
Animal Clinic of Regina · Canada
Species:
dog

Plain-English summary

A 10-year-old spayed female Golden Retriever was brought in because she had been limping on her right back leg for a long time. About three years earlier, she had surgery called a tibial plateau leveling osteotomy (TPLO) to help with her knee. Recently, a soft tissue lump that was growing on her right knee was tested and found to be a type of cancer called histiocytic sarcoma. The study mentions possible connections between this kind of cancer and factors like long-term joint inflammation, previous surgeries, and the specific plate used in her surgery. The outcome of the treatment for the cancer is not provided in the abstract.

Abstract

A 10-year-old spayed female Golden Retriever was admitted with chronic lameness of the right hind limb. A tibial plateau leveling osteotomy (TPLO) had been performed on this leg approximately three years previously. A progressively growing soft tissue mass, affecting the right stifle, previously treated with TPLO was biopsied and found to be a histiocytic sarcoma. Previously proposed links between the development of neoplasia in the stifle region and the presence of chronic synovitis, osteotomy, orthopaedic implants, and specifically the Slocum TPLO plate, are briefly discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18704246/