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Peer-reviewed veterinary case report

Histiocytic ulcerative colitis in three non-boxer dogs.

Journal:
Journal of the American Animal Hospital Association
Year:
2001
Authors:
Stokes, J E et al.
Affiliation:
Department of Small Animal Clinical Sciences · United States
Species:
dog

Abstract

Histiocytic ulcerative colitis (HUC) is described in three non-boxer dogs. Clinical signs were typical of large-bowel diarrhea and included soft stool, hematochezia, tenesmus, and an increased frequency of defecation. Diagnosis in each case was made by light microscopic evaluation of endoscopically obtained colonic biopsy specimens. Treatment regimes varied, but included immunosuppressive agents, anti-inflammatory drugs, antimicrobials, and dietary modification. Clinical response was substantial in two patients, while the third patient was euthanized due to treatment failure. The authors' observations indicate that HUC may be encountered in non-boxer dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/11563445/