Peer-reviewed veterinary case report
Cat brain tumor (ependymoma) found in fourth ventricle and studied
By McKay, J S et al.·Published in Journal of comparative pathology·1999·Department of Veterinary Pathology, United Kingdom·View original on PubMed →
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Original publication title: Histological characterization of an ependymoma in the fourth ventricle of a cat.
- Species:
- cat
Plain-English summary
A 3-year-old cat was diagnosed with a tumor in the fourth ventricle of its brain, which was surgically removed. The tumor was identified as a tanycytic ependymoma, a type of brain tumor that had not been previously reported in pets. The tumor's characteristics were similar to those found in humans, and specific tests showed that the tumor cells reacted positively to certain proteins. After surgery, the cat's condition and recovery details were not provided, but surgical removal is typically the first step in treating such tumors.
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Abstract
A tumour occupying the fourth ventricle in a 3-year-old cat was removed surgically and characterized as a tanycytic ependymoma on the basis of histological features of low cellularity, inconspicuous perivascular pseudorosettes and fascicular architecture. Immunohistochemical analysis of sections revealed that the neoplastic cells were immunoreactive for glial fibrillary acidic protein (GFAP), vimentin and S-100. The histological and immunohistochemical findings were similar to those of human tanycytic ependymoma, a subclassification of ependymoma not previously described in domestic species.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10098020/