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Peer-reviewed veterinary case report

Heart defects with abnormal tissue found in 6-week-old Labrador puppy

By Schoebel, J et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2025·Small Animal Clinic, Germany·View original on PubMed

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Original publication title: Histological evidence of myxomatous tissue in a Labrador puppy with pulmonic stenosis and tricuspid valve dysplasia.

Species:
dog

Plain-English summary

A six-week-old Labrador puppy was brought to the vet because he was lethargic and not eating well. During the examination, the vet discovered a heart murmur and diagnosed him with tricuspid valve dysplasia (a heart valve problem) and pulmonic stenosis (narrowing of a heart valve). Further tests showed unusual tissue changes in the heart valves. The puppy's condition is serious, and he may need specialized treatment to manage these heart issues.

People also search for: puppy lethargy and not eating · Labrador heart murmur treatment · tricuspid valve dysplasia in dogs

Abstract

A six-week-old Labrador retriever was presented for lethargy and anorexia, revealing a systolic heart murmur. Tricuspid valve dysplasia involving the whole tricuspid valve apparatus and the right ventricular wall was found, and an additional pulmonic stenosis was present. Histopathological examination of the tricuspid and pulmonary leaflets highlighted an unusual myxomatous mesenchymal component, interpreted as being of ontogenetic origin.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40882472/