Peer-reviewed veterinary case report
Healing after nonsurgical gum treatment with enamel matrix in dogs
By Shujaa Addin, Ammar et al.·Published in Odontology·2018·Department of Periodontology, Japan·View original on PubMed →
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Original publication title: Histological healing after nonsurgical periodontal treatment with enamel matrix derivatives in canine experimental periodontitis.
- Species:
- dog
Plain-English summary
A group of six beagle dogs with gum disease underwent a nonsurgical treatment involving scaling and root planing, along with a special gel called enamel matrix derivatives (EMD). After 11 weeks, the dogs showed no significant differences in gum depth or attachment levels between those treated with EMD and those treated with a saline solution. However, the dogs that received EMD had more new cementum (the tissue that helps anchor teeth) and less unwanted gum growth compared to the control group. This suggests that EMD may help improve healing in dogs with periodontal disease when used alongside standard treatments.
People also search for: dog gum disease treatment · beagle periodontal disease · enamel matrix derivatives for dogs
Abstract
The histological outcomes after nonsurgical periodontal treatment with enamel matrix derivatives (EMD) remain controversial. The present study evaluated periodontal wound healing after scaling and root planing (SRP) with subgingival application of EMD for treatment of experimental periodontitis. Periodontal breakdown was induced by applying silk ligatures around mandibular third and fourth premolars of six beagle dogs until radiographic bone loss progressed to approximately half of the root length. Probing pocket depth (PPD) and clinical attachment level (CAL) were proximally measured 2 weeks after ligature removal (baseline). Mesial and distal surfaces of the experimental teeth were subjected to SRP and randomized using a split-mouth design to subgingival application of EMD (test) or normal saline (control). PPD and CAL were re-evaluated at 11 weeks. Animals were sacrificed at 12 weeks for histological analyses. No significant differences were observed in PPD and CAL between both groups at baseline and at 11 weeks. Histologically, test sites exhibited a greater amount of new cementum than that did the control sites (p < 0.01). Moreover, the control sites revealed increased epithelial downgrowth compared with the test sites: (p < 0.05). On the other hand, no intergroup differences were detected in terms of bone position, connective tissue attachment, gingival recession, and planed root length. This study suggested that EMD has an increased potential to support formation of new cementum with decreased epithelial downgrowth when used as an adjunct to nonsurgical periodontal treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29429056/