Peer-reviewed veterinary case report
Medullary thyroid cancer with lung spread in a young dog
By Piñeyro, Pablo et al.·Published in Journal of veterinary science·2014·Department of Biomedical Sciences and Pathobiology and 3Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Histopathological and immunohistochemical findings of primary and metastatic medullary thyroid carcinoma in a young dog.
- Species:
- dog
Plain-English summary
A young dog was diagnosed with medullary thyroid carcinoma (MTC), a type of cancer affecting the thyroid gland, which had spread to the lungs. The tumor was made up of abnormal cells and showed specific markers that confirmed the diagnosis. Identifying this type of cancer can be challenging, as it can resemble other thyroid tumors. Unfortunately, the report does not provide information on treatment or the outcome for this dog.
People also search for: dog thyroid cancer symptoms · young dog lung cancer treatment · medullary thyroid carcinoma in dogs
Abstract
This report describes the gross, histological, and immunohistochemical features of medullary thyroid carcinoma (MTC) with pulmonary metastases in a young dog. Sheets of pleomorphic cells supported by fibrous stroma characterized the primary mass, while metastatic nodules had a neuroendocrine pattern. Despite differing histologic features, all masses showed marked immunoreactivity against calcitonin and multiple neuroendocrine markers consistent with MTC. Although MTC is a well-recognized entity, it may be difficult to distinguish this mass from other thyroid neoplasms, necessitating immunohistochemical characterization.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24690600/