Peer-reviewed veterinary case report
Histopathological and immunohistochemical findings of primary and metastatic medullary thyroid carcinoma in a young dog.
- Journal:
- Journal of veterinary science
- Year:
- 2014
- Authors:
- Piñeyro, Pablo et al.
- Affiliation:
- Department of Biomedical Sciences and Pathobiology and 3Small Animal Clinical Sciences · United States
- Species:
- dog
Abstract
This report describes the gross, histological, and immunohistochemical features of medullary thyroid carcinoma (MTC) with pulmonary metastases in a young dog. Sheets of pleomorphic cells supported by fibrous stroma characterized the primary mass, while metastatic nodules had a neuroendocrine pattern. Despite differing histologic features, all masses showed marked immunoreactivity against calcitonin and multiple neuroendocrine markers consistent with MTC. Although MTC is a well-recognized entity, it may be difficult to distinguish this mass from other thyroid neoplasms, necessitating immunohistochemical characterization.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24690600/