Peer-reviewed veterinary case report
Common skin tumor in young dogs that often goes away on its own
By Pires, Isabel et al.·Published in Cells·2024·University of Trá·View original on PubMed →
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Original publication title: Histopathological and Ultrastructural Study of a Canine Langerhans Cell Tumour (Canine Cutaneous Histiocytoma).
- Species:
- dog
Plain-English summary
A young dog under four years old was found to have a skin tumor called a canine cutaneous histiocytoma, which is a common type of skin growth in dogs. These tumors usually appear as single lumps and can sometimes go away on their own. In a study of 93 cases, researchers looked closely at the tumors and found that they often showed signs of inflammation and changes in the skin structure. Most of these tumors had some level of cell death and unusual cell features. Understanding these characteristics can help veterinarians diagnose and manage this common skin issue in dogs.
People also search for: dog skin tumor treatment · canine cutaneous histiocytoma symptoms · young dog lump on skin
Abstract
Canine cutaneous histiocytoma (CCH) represents a significant proportion of dog skin tumours, often manifesting as the most common neoplastic skin condition in young animals. Predominantly affecting dogs under four, these tumours appear primarily as solitary lesions that may regress spontaneously. This study, conducted over five years at the University of Trás-os-Montes e Alto Douro, involved a detailed histopathological and ultrastructural examination of 93 CCH cases. Histologically, these tumours showed distinct patterns of lymphoid infiltration, which contributed to their classification into four groups based on the inflammatory response and histological architecture. Most tumours displayed signs of epidermal invasion and frequent mitotic figures, with necrosis present in over half of the cases. Ultrastructurally, the neoplastic cells were characterised by pleomorphism, abundant organelles, and adherens-type junctions. This study offers significant insights into the pathophysiology and morphological characteristics of CCH, underscoring the importance of detailed histological and ultrastructural analysis in accurately diagnosing and understanding this common canine tumour.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39120294/