Peer-reviewed veterinary case report
Pancreas damage from low blood flow in dogs with heart failure
By Yoshimura, Aritada et al.·Published in The Journal of veterinary medical science·2021·Tokyo University of Agriculture and Technology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Histopathological changes in the pancreas due to decreased pancreatic blood flow in a canine tachycardia-induced cardiomyopathy model.
- Species:
- dog
Plain-English summary
A dog with heart failure due to tachycardia (rapid heartbeat) showed signs of pancreatic injury after four weeks of treatment. The decreased blood flow to the pancreas led to atrophy of the pancreatic acinar cells, which are important for producing digestive enzymes. This suggests that heart problems can negatively affect the pancreas, potentially leading to further health issues. It's important for pet owners to be aware of these connections and discuss any concerns about their dog's heart and digestive health with their veterinarian.
People also search for: dog heart failure symptoms · pancreatic injury in dogs · tachycardia treatment for dogs
Abstract
In dogs, pancreatic acinar cell injury is thought to be caused by decreased pancreatic blood flow due to heart failure. In previous our report, it demonstrated that decreased heart function causes a significant decrease in pancreatic blood flow in heart failure dog model caused by rapid ventricular pacing (RVP). However, the types of histopathological changes remain unclear. We aimed to verify the types of histopathological changes occurring in the pancreatic tissue due to decreased heart function. After RVP for 4 weeks, atrophy of pancreatic acinar cells, characterized by a decrease in zymogen granules, was observed in all areas of the pancreas. In conclusion, the result of this study suggests that attention should be paid to ischemia/hypoperfusion injury in the pancreas.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33716230/