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Peer-reviewed veterinary case report

Fungal eye infection keratomycosis in a dog and treatment steps

By Rampazzo, Antonella et al.·Published in Veterinary ophthalmology·2009·Department of Clinical Veterinary Medicine·View original on PubMed

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Original publication title: Hormographiella aspergillata keratomycosis in a dog.

Species:
dog

Plain-English summary

A 4-year-old female Border Collie was brought to the vet with a corneal lesion that had been present for 10 days. The vet found a whitish plaque on the dog's cornea and diagnosed her with a fungal eye infection called keratomycosis. Initial treatment with antibiotics and fluconazole didn't improve her condition, so the vet performed surgery to remove the affected tissue and repair the eye. After the surgery, her cornea healed well, and the specific fungus causing the infection was identified using advanced genetic testing.

People also search for: dog eye infection treatment · Border Collie corneal lesion · keratomycosis in dogs · dog fungal eye infection symptoms

Abstract

A 4-year-old, female, Border Collie was presented to the University of Bern Veterinary Teaching Hospital, because of a corneal lesion of 10 days duration. The axial cornea presented a whitish fluorescein-positive plaque with irregular margins. A diagnosis of keratomycosis was made based on cytology. Medical therapy with local broad-spectrum antibiotic and fluconazole was instituted. After 1 week of treatment, the improvement was deemed unsatisfactory. Therefore, a lamellar keratectomy and conjunctival pedicle flap were performed. After surgery, the cornea healed uneventfully. Histology confirmed the diagnosis of keratomycosis. The fungus could not be grown in culture and a precise etiological diagnosis could only be obtained with genetic identification of the fungus. A PCR technique was used to amplify the fungal genome from the cornea. Hormographiella aspergillata, the asexual reproductive form of the basidiomycete Coprinopsis cinerea, was identified. As advised in human medicine, we encourage the use of this molecular technique to obtain an early species diagnosis, allowing targeted medical therapy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19152597/