Peer-reviewed veterinary case report
Cat with adrenal tumor causing high progesterone and hormone issues
By Rossmeisl, J H et al.·Published in Journal of the American Animal Hospital Association·2000·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Hyperadrenocorticism and hyperprogesteronemia in a cat with an adrenocortical adenocarcinoma.
- Species:
- cat
Plain-English summary
A 7-year-old neutered male domestic shorthair cat was brought in for poorly controlled diabetes and fragile skin. Tests showed a tumor on the right adrenal gland, but the usual hormone levels for Cushing's disease (hyperadrenocorticism) were normal. Instead, high levels of progesterone were found, which were linked to the cat's symptoms. Sadly, the cat was diagnosed with an adrenal tumor (adrenocortical adenocarcinoma) after passing away, and it was confirmed that the tumor was producing progesterone.
People also search for: cat skin problems · cat diabetes treatment · adrenal tumor in cats · hyperprogesteronemia in cats
Abstract
A seven-year-old, neutered male domestic shorthair cat was evaluated for poorly regulated diabetes mellitus and increased skin fragility. Imaging studies revealed a right adrenal gland tumor, but cortisol testing did not support a diagnosis of hyperadrenocorticism. Serum concentrations of progesterone and testosterone were increased compared with a group of normal cats, and the clinical signs were attributed to hyperprogesteronemia. At necropsy, a diagnosis of adrenocortical adenocarcinoma was confirmed, and immunohistochemical staining confirmed the presence of progesterone within the tumor. Clinical signs of hyperadrenocorticism in cats may occur due to increased serum concentrations of hormones other than cortisol.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11105888/