Peer-reviewed veterinary case report
Hyperadrenocorticism with sex hormone imbalance in dogs
By Greco, Deborah S·Published in Clinical techniques in small animal practice·2007·Nestle Purina Petcare, United States·View original on PubMed →
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Original publication title: Hyperadrenocorticism associated with sex steroid excess.
- Species:
- dog
Plain-English summary
A 7-year-old neutered male Miniature Poodle was brought in for hair loss on its back and sides, which is a sign of a hormone imbalance known as sex steroid excess. Unlike typical Cushing's disease, this condition can cause different symptoms, such as growths around the rear end. The vet found elevated liver enzymes in the blood tests, indicating liver stress. Treatment options include medication, surgery, or radiation, depending on the severity of the condition. With appropriate treatment, many dogs can see improvements in their symptoms.
People also search for: dog hair loss treatment · Miniature Poodle hormone imbalance · perianal adenomas in dogs · elevated liver enzymes in dogs · Cushing's disease symptoms in dogs
Abstract
Diagnosis of sex steroid excess or hyperadrenocorticism in dogs may be challenging. Unlike Cushing's disease, sex steroid excess may have a multitude of manifestations that differ from standard hyperadrenocorticism. In particular, the clinical scenario of a dog with sex steroid imbalance involves one of three systems: dermatologic, reproductive, or hepatic. The history of a dog with hyperadrenocorticism manifesting as sex steroid imbalance often lacks the classical clinical signs of polydipsia and polyuria. Dogs with sex steroid imbalance will often be of specific breeds such as miniature poodles and exhibit trunkal hair loss as the only sign. There is often involvement of the reproductive system, manifested as the growth of perianal adenomas in neutered male or female dogs. The most common laboratory findings consist of elevations in serum alkaline phosphatase and serum alanine transferase. The following article reviews the etiology, common signalment, clinical signs, and laboratory findings associated with atypical hyperadrenocorticism caused by sex steroid imbalance and then explores the medical, surgical, and radiation treatment options.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17542192/