Peer-reviewed veterinary case report
Cat with hyperadrenocorticism treated with metyrapone
By Moore, L E et al.·Published in Journal of the American Veterinary Medical Association·2000·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Hyperadrenocorticism treated with metyrapone followed by bilateral adrenalectomy in a cat.
- Species:
- cat
Plain-English summary
A 6-year-old spayed female cat was brought in for uncontrolled diabetes and a poor coat. Tests showed high liver enzymes, high blood sugar, and large adrenal glands, leading to a diagnosis of hyperadrenocorticism (Cushing's disease). The vet first treated her with metyrapone, which helped stabilize her condition, and then performed surgery to remove both adrenal glands. After the surgery, the cat recovered well and has been doing fine for the past five months with ongoing medication.
People also search for: cat diabetes treatment · hyperadrenocorticism in cats · cat adrenal gland surgery · metyrapone for cats · cat hair coat problems
Abstract
A 6-year-old spayed female cat was evaluated for uncontrolled diabetes mellitus and poor hair coat. Clinicopathologic abnormalities included high serum activity of liver enzymes, hyperglycemia, hypercholesterolemia, glucosuria, and an exaggerated response to ACTH stimulation. Abdominal ultrasonography revealed large adrenal glands. Hyperadrenocorticism was diagnosed. Treatment for a facial abscess was instituted along with administration of metyrapone for hyperadrenocorticism. After stabilization, bilateral adrenalectomy was performed. The cat recovered without complications and has remained clinically normal for 5 months with treatment of desoxycorticosterone pivalate and prednisone. Treatment with metyrapone appeared to stabilize the cat metabolically and clinically prior to surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10976301/