Peer-reviewed veterinary case report
High ammonia levels linked to kidney disease in cats
By Adagra, Carl & Foster, Darren J·Published in Journal of feline medicine and surgery·2015·School of Veterinary and Biomedical Sciences, Australia·View original on PubMed →
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Original publication title: Hyperammonaemia in four cats with renal azotaemia.
- Species:
- cat
Plain-English summary
Four cats with severe kidney disease were found to have high ammonia levels during treatment. Two of these cats showed neurological symptoms, which can include confusion or disorientation, suggesting that the elevated ammonia might be linked to these issues. This finding indicates that high ammonia levels could contribute to brain problems in cats suffering from kidney disease. It's important for pet owners to be aware of this potential complication and discuss it with their veterinarian if their cat has kidney issues.
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Abstract
Hyperammonaemia is well reported in animals with advanced hepatic disease and portosystemic shunts, but is unreported in cats with renal disease. This case series describes four cats with severe renal azotaemia in which elevated ammonia levels were detected during the course of treatment. In two cases hyperammonaemia was detected at a time when neurological signs consistent with encephalopathy had developed. This raises the possibility that hyperammonaemia may play a role in the development of encephalopathy in cats with renal azotaemia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24626464/