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Peer-reviewed veterinary case report

Hypercalcemia and hypophosphatemia in a mare with renal insufficiency.

Journal:
Journal of the American Veterinary Medical Association
Year:
1978
Authors:
Brobst, D F et al.
Species:
horse

Plain-English summary

An 11-year-old female horse was experiencing symptoms like peeing and drinking a lot, along with signs of kidney problems. Tests showed that she had high calcium levels and low phosphate levels in her blood. Even though her urine calcium levels were normal, the phosphate levels were low. After receiving some supportive care, the mare sadly passed away, and a post-mortem examination revealed that her kidneys were shrunken and had signs of damage typical of glomerulonephritis (inflammation of the kidney's filtering units). Unfortunately, the treatment did not save her.

Abstract

An 11-year-old mare with polyuria, polydipsia, and azotemia was found to be hypercalcemic and hypophosphatemic. The concentration of calcium in a single collection of urine was within normal limits, although urinary inorganic phosphate concentration was lower than normal. After a brief period of supportive treatment, the mare died. At necropsy, the kidneys were found to be shrunken and fibrous. Histologically, the lesions were those of glomerulonephritis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/730618/