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Peer-reviewed veterinary case report

Hypercholesterolaemia in a family of rough collie dogs.

Journal:
The Journal of small animal practice
Year:
2004
Authors:
Jeusette, I et al.
Affiliation:
Veterinary Faculty
Species:
dog

Abstract

A family of five privately owned rough collie dogs was referred for corneal lipidosis and also suffered from hypercholesterolaemia. The hypercholesterolaemia was characterised by an increase in the alpha-2 high density lipoprotein-1 band and was due to an increase in the cholesterol content of the very low density lipoprotein, low density lipoprotein and possibly the high density lipoprotein-1 fractions. A low-fat and energy-restricted diet did not reduce either total cholesterol or the corneal lipidosis. Corneal lipidosis regressed with short-chain fructo-oligosaccharide supplementation. However, the effects of short-chain fructo-oligosaccharides on total cholesterol were transient and variable.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15206480/