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Peer-reviewed veterinary case report

High cholesterol and corneal lipidosis in rough collie dogs

By Jeusette, I et al.·Published in The Journal of small animal practice·2004·Veterinary Faculty·View original on PubMed

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Original publication title: Hypercholesterolaemia in a family of rough collie dogs.

Species:
dog

Plain-English summary

A family of five rough collie dogs was brought in for eye problems caused by corneal lipidosis, which is a condition where fat builds up in the eyes, along with high cholesterol levels. The dogs were put on a low-fat diet, but this did not help lower their cholesterol or improve their eye condition. However, adding a supplement called short-chain fructo-oligosaccharides did help reduce the eye problems, although the effect on cholesterol levels was temporary and varied.

People also search for: rough collie eye problems · dog high cholesterol treatment · corneal lipidosis in dogs · dog diet for high cholesterol

Abstract

A family of five privately owned rough collie dogs was referred for corneal lipidosis and also suffered from hypercholesterolaemia. The hypercholesterolaemia was characterised by an increase in the alpha-2 high density lipoprotein-1 band and was due to an increase in the cholesterol content of the very low density lipoprotein, low density lipoprotein and possibly the high density lipoprotein-1 fractions. A low-fat and energy-restricted diet did not reduce either total cholesterol or the corneal lipidosis. Corneal lipidosis regressed with short-chain fructo-oligosaccharide supplementation. However, the effects of short-chain fructo-oligosaccharides on total cholesterol were transient and variable.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15206480/