Peer-reviewed veterinary case report
High blood ferritin levels in dogs with splenic hemangiosarcoma
By Chikazawa, Seishiro et al.·Published in The Journal of veterinary medical science·2013·Department of Small Animal Internal Medicine, Japan·View original on PubMed →
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Original publication title: Hyperferritinemia in dogs with splenic hemangiosarcoma.
- Species:
- dog
Plain-English summary
A group of dogs with splenic masses, including 11 with a type of cancer called hemangiosarcoma, had their blood tested for ferritin levels, a protein that can indicate disease. All the dogs with hemangiosarcoma showed very high ferritin levels, which could help vets identify this serious condition. While elevated ferritin was also seen in some dogs with other conditions, it appears to be a useful marker for hemangiosarcoma. More research is needed to fully understand how ferritin levels can aid in diagnosing this cancer in dogs.
People also search for: dog splenic mass symptoms · high ferritin in dogs · hemangiosarcoma treatment in dogs
Abstract
Serum ferritin concentration increases in dogs in association with various diseases. In this study, we measured serum ferritin levels in dogs with splenic masses, using a sandwich ELISA assay. Eleven dogs with hemangiosarcoma (HSA), six with hematoma, 1 with hemangioma and 3 with lymphoma were enrolled. All dogs with HSA had serum ferritin concentrations above the normal limit (1,357 ng/ml, mean + 2× standard deviation of normal). Increased serum ferritin concentrations have also been observed in few cases of hematoma, hemangioma and lymphoma. Therefore, hyperferritinemia is not specific for splenic HSA, but may have clinical usefulness as a sensitive test for the disease. Further evaluation of serum ferritin concentrations in dogs with splenic HSA is needed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23803459/