Peer-reviewed veterinary case report
Hypermutations in porcine respiratory and reproductive syndrome virus.
- Journal:
- Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
- Year:
- 2019
- Authors:
- Dong, Jianguo et al.
- Affiliation:
- School of Animal Husbandry and Medical Engineering · United Kingdom
Abstract
Porcine reproductive and respiratory syndrome (PRRS), which is caused by the PRRS virus (PRRSV), has resulted in large economic losses for the swine industry. The virus has shown remarkable genetic diversity since its discovery. In our study, we investigated mutation types in the evolution of PRRSV for bothandpassaging of the virus. Sequence alignment analysis demonstrated that the most common hypermutations expressed were A→G/U→C and G→A/C→U. The data provide a new theoretical basis for PRRSV evolution.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31097872/